Did you know about the Renal replacement therapy?

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Renal replacement therapy (RRT) is the therapy that follows normal blood-filtering function of the kidneys. It is used once the kidneys don't seem to be operating well that is termed as renal failure and it includes acute kidney injury and chronic kidney disease. Renal replacement medical aid includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration that measure numerous ways of filtration of blood with or with not machines. Renal replacement medical aid conjointly includes kidney transplantation, which is the final variety of replacement in this; the previous kidney is replaced by a donor kidney.

Renal replacement therapy is indicated, when the kidney briefly or persistently loses its function to remove toxins, metabolites, and water from the body. It is also used in some specific cases of poisoning/overdose when the kidney cannot clear the toxin fast enough. There are three main modalities used to replace the renal function: dialysis (either hemodialysis or peritoneal dialysis), hemofiltration, and kidney transplant .Dialysis is based on the diffusion of molecules across a semipermeable membrane, which detaches blood on one side and the dialysate on the other. Hemofiltration is placed upon the principles of filtration and convection, (as opposed to diffusion) and mimics the function of the glomerular system. An ultra-filtrate is excreted, and the replacement of electrolytes with a specific solution is essential. Kidney transplantation is pointed out for patients with end-stage renal disease (ESRD). In those cases, it is associated with a greater long-term survival rate and a better quality of life than dialysis.

Different type of renal replacement therapy:

·         Peritoneal dialysis (PD)

·         Intermittent hemodialysis (IHD)

·         Continuous renal replacement therapies (CRRT).

·         Continuous hemofiltration (CHF)

·         Continuous hemodialysis (CHD)


·         Continuous hemodiafiltration (CHDF)

·         Intermittent renal replacement therapy (IRRT)

 Intermittent hemodiafiltration (IHDF) 

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